MICROBIOLOGIA E IGIENEModule MICROBIOLOGIA E MICROBIOLOGIA CLINICA
Academic Year 2022/2023 - Teacher: Adriana GAROZZOExpected Learning Outcomes
The student must learn the biological and pathogenic characteristics of microorganisms that play a role in human pathology, with reference to bacteria, viruses and fungi. He must acquire appropriate knowledge on the relationships between microorganisms and host in normal and pathological conditions, identify the transmission pathways, know the characteristics, the activity, the mechanism of action and resistance of the main antimicrobial drugs and vaccines. The student must also know the main methods for the cultivation and identification of microorganisms.
The course also aims to illustrate the various methods of prevention of microbial infections and the main causes of infection related to specific professional activity.
Course Structure
Traditional lectures, with the support of slides and educational videos of some theoretical-practical teaching topics (the films will be available on the Studium page). Students during one of the last lessons will have the opportunity to view some practical activities carried out in the laboratories of Microbiology.
Detailed Course Content
- Introduction to medical microbiology: microorganism-host relationships.
- The organization of the bacterial cell: structure and function of the cellular components
- Mechanisms of bacterial pathogenesis: role of bacteria in disease
- The antimicrobial chemotherapy: the main characteristic of principal groups of antibiotics and the antibiotic resistance
- Characteristics of virus and their replication
- Mechanisms of viral pathogenesis
- Types of viral infection: acute and persistent infection
- The antiviral chemotherapy
- Characteristics of fungi and their metabolism
- Mechanisms of fungal pathogenesis
- Antimicrobial vaccines
- General principles of laboratory diagnosis of infectious diseases
- General principles of sterilization, disinfection, and antisepsis
- The main human pathogen microorganisms
- Nosocomial infections
Textbook Information
EUDES LANCIOTTI - “ Microbiologia clinica” - 4° Edizione - Casa Editrice Ambrosiana.
Course Planning
| Subjects | Text References | |
|---|---|---|
| 1 | Introduzione alla Microbiologia: agenti patogeni, rapporto microrganismo-ospite. | Capitolo 1 |
| 2 | La cellula batterica: struttura, crescita e metabolismo. | Capitolo 3: da 3.1 a 3.5 e 3.8 |
| 3 | Azione patogena dei batteri. | Capitolo 3 (3.9 e 3.10) |
| 4 | Principi del meccanismo di azione dei farmaci antibatterici e meccanismi di resistenza. | Capitolo 7 (7.1) |
| 5 | Caratteristiche generali dei miceti. | Capitolo 4 (4.1, 4.2) |
| 6 | Azione patogena dei miceti e malattie da funghi | Capitolo 4 (4.3 e 4.4) |
| 7 | I Virus: struttura e replicazione. | Capitolo 6 (6.1, 6.2, 6.3) |
| 8 | Azione patogena dei virus ed effetti dell'infezione virale sull'ospite. | Capitolo 6 (6.4) |
| 9 | Principi del meccanismo di azione dei principali farmaci antivirali. | Capitolo 6 (6.5) |
| 10 | Vaccini | Capitolo 9 (9.2) |
| 11 | Principi generali di diagnostica di laboratorio delle malattie infettive. | Capitoli 2, 10, 11 |
| 12 | Principi di disinfezione e sterilizzazione. | Capitolo 7 (7.4) |
| 13 | Principali microrganismi patogeni per l'uomo | Capitolo 13 |
| 14 | Infezioni nosocomiali | Appendice in ebook E9 |