Academic Year 2023/2024 - Teacher: Adriana GAROZZO

Expected Learning Outcomes

The student must learn the biological and pathogenic characteristics of microorganisms that play a role in human pathology, with reference to bacteria, viruses and fungi. He must acquire appropriate knowledge on the relationships between microorganisms and host in normal and pathological conditions, identify the transmission pathways, know the characteristics, the activity, the mechanism of action and resistance of the main antimicrobial drugs and vaccines. The student must also know the main methods for the cultivation and identification of microorganisms.

The course also aims to illustrate the various methods of prevention of microbial infections and the main causes of infection related to specific professional activity.

Course Structure

Traditional lectures, with the support of slides and educational videos of some theoretical-practical teaching topics (the films will be available on the Studium page). Students during one of the last lessons will have the opportunity to view some practical activities carried out in the laboratories of Microbiology.

Detailed Course Content

  1. Introduction to medical microbiology: microorganism-host relationships.
  2. The organization of the bacterial cell: structure and function of the cellular components
  3. Mechanisms of bacterial  pathogenesis: role of bacteria in disease 
  4. The antimicrobial chemotherapy: the main characteristic of principal groups of antibiotics and the antibiotic resistance
  5. Characteristics of virus and their replication
  6. Mechanisms of viral pathogenesis
  7. Types of viral infection: acute and persistent infection
  8. The antiviral chemotherapy
  9. Characteristics of fungi and their metabolism
  10. Mechanisms of fungal pathogenesis
  11. Antimicrobial vaccines
  12. General principles of laboratory  diagnosis of infectious diseases
  13. General principles of sterilization, disinfection, and  antisepsis
  14. The main human pathogen microorganisms
  15. Nosocomial infections

Textbook Information

EUDES LANCIOTTI  - “ Microbiologia clinica” - 4° Edizione - Casa Editrice Ambrosiana.

Course Planning

 SubjectsText References
1Introduzione alla Microbiologia: agenti patogeni, rapporto microrganismo-ospite.Capitolo 1
2La cellula batterica: struttura, crescita e metabolismo.Capitolo 3: da 3.1 a 3.5 e 3.8
3Azione patogena dei batteri.Capitolo 3 (3.9 e 3.10)
4Principi del meccanismo di azione dei farmaci antibatterici e meccanismi di resistenza.Capitolo 7 (7.1)
5Caratteristiche generali dei miceti.Capitolo 4 (4.1, 4.2)
6Azione patogena dei miceti e malattie da funghiCapitolo 4 (4.3 e 4.4)
7I Virus: struttura e replicazione.Capitolo 6 (6.1, 6.2, 6.3)
8Azione patogena dei virus ed effetti dell'infezione virale sull'ospite.Capitolo 6 (6.4)
9Principi del meccanismo di azione dei principali farmaci antivirali.Capitolo 6 (6.5)
10VacciniCapitolo 9 (9.2)
11Principi generali di diagnostica di laboratorio delle malattie infettive.Capitoli 2, 10, 11
12Principi di disinfezione e sterilizzazione.Capitolo 7 (7.4)
13Principali microrganismi patogeni per l'uomoCapitolo 13
14Infezioni nosocomialiAppendice in ebook E9