Microbiology and HYGIENE
Module MICROBIOLOGIA E MICROBIOLOGIA CLINICA

Academic Year 2022/2023 - Teacher: Maria Antonietta TOSCANO

Expected Learning Outcomes

Provide basic knowledge about microorganisms and their role as human pathogens.

Provide basic knowledge on the microbial pathogenicity, on the host-parasite

relationships and on the interactions between microorganisms and antimicrobial

agents. Provide knowledge on the general principles of prophylaxis and of diagnosis

of infectious diseases, with particular attention to odontostomatologic diseases.

Course Structure

Should teaching be carried out in mixed mode or remotely, it may be necessary to introduce changes with respect to previous statements, in line with the programme planned and outlined in the syllabus.

Learning assessment may also be carried out on line, should the conditions require it.”

Detailed Course Content

BACTERIOLOGY

a) Essential characteristics of bacteria known to infect humans.

b) Most important groups of bacteria and related diseases

VIROLOGY :       

a) Essential characteristics of bacteria known to infect humans.

b) Most important groups of viruses and related diseases

MYCOLOGY AND PARASITOLOGY :

a) Essential characteristics of fungi and protozoa known to infect humans.

b) Most important groups of fungi/parasites and related diseases

MICROORGANISM-HOST RELATIONSHIPS:                                         

a) The microbial population normally resident in the human body.

b) The pathogenic mechanisms of microorganisms.

c) The various possibilities of infection and spread of infection.

INFECTION CONTROL: 

General concepts about disinfection, asepsys, antisepsys and sterilization  (physical, chemical and biological methods)

History, meanings  and objectives of antimicrobial chemotherapy.

a) Antibacterial chemotherapy (Classification and key characteristics of main groups of antibiotics, Mechanism of action, antibiotic resistance)

b) Antiviral chemotherapy (Classification, Mechanism of action and resistance,Combined therapies)

c) Antifungal drugs (Classification, Mechanism of action and resistance)

d) Prevention (immune sera and human vaccines )

CLINICAL MICROBIOLOGY IN DENTAL CARE

Ecological characteristics of oral cavity and microbioma. Principal microrganisms representative of oral cavity and of its patological involvement in periodontisis.

Oral streptococci.  Role of bacterial factors in microbial adherence, interaction among microorganisms, onset of microbial flora in oral cavity, 

Dental plaque: acquisition, evolution, composition, variations, microbial interactions, biochemical implications and mineralization.

Dental caries: aetiological theories, carie as infectious disease. Principal bacteria responsible.

Prevention of caries, Microbiological aspects of periodontal diseases, Therapeutic approaches to principal infectious diseases and infective processes of  oral cavity.

Principal groups of microbial pathogens (bacteria, virus, fungi and protozoa) expecially in odontoiatric field.

Textbook Information

-La Placa – Principi di Microbiologia Medica – Società Editrice Esculapio. 

-Murray P. R., Rosenthal K. S., Pfaller M. – Microbiologia medica - EMSI - 

-Lakshman Samaranayake – Essential Microbiology for Dentistry – Third edition – Churchill Livingstone, ELSEVIER. 

-Lamont R.J., Burne R.A.,Lantz M.S., LeBlanc D.J. – Microbiologia ed immunologia del cavo orale – EMSI 

-Elliott T., Worthington T., Osman H., Gill M. – Microbiologia medica ed infezioni – Quarta edizione EMSI 

Course Planning

 SubjectsText References
1Tossicità selettiva
2Meccanismi d'azione dei chemioantibiotici
3Principali gruppi di chemioantibiotici
4Resistenze plasmidiali e cromosomiali
5Meccanismi genetici di resistenza
6Espressione fenotipica delle resistenze
VERSIONE IN ITALIANO